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Three sesquiterpenes from the marine-alga-epiphytic fungus Trichoderma hamatum Z36-7
- Source :
- Phytochemistry Letters. 43:98-102
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Two new cyclonerane sesquiterpenes, 5-hydroxyepicyclonerodiol oxide (1) and 4-hydroxyepicyclonerodiol oxide (2), and one new naturally occurring halogenated trichothecane derivative, trichodermol chlorohydrin (3), were isolated from Trichoderma hamatum Z36−7, an epiphytic fungal strain obtained from the marine red alga Grateloupia sp. Their structures and relative configurations were assigned on the basis of spectroscopic techniques, including 1D/2D NMR and IR as well as MS. Compound 2 features an unusual 4-hydroxy group on the five-membered ring of cycloneranes, and 3 is the first natural isolate of halogenated trichothecanes. These isolates represent the first occurrence of terpenes in T. hamatum and exhibit growth inhibition of several bacteria and phytoplankton species.
Details
- ISSN :
- 18743900
- Volume :
- 43
- Database :
- OpenAIRE
- Journal :
- Phytochemistry Letters
- Accession number :
- edsair.doi...........ff13b08bf121777ef8e89f7c0fb33893