Back to Search
Start Over
Premature ovarian failure treated with mild moxibustion and western medication
- Source :
- World Journal of Acupuncture - Moxibustion. 31:291-295
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Objective To explore the clinical therapeutic effect on premature ovarian failure (POF) treated with the combination of mild moxibustion and western medication. Methods A total of 66 patients were divided into a control group and an observation group according to random number table, 33 cases in each one. In the control group, the conventional western medication was administered. In the observation group, besides the treatment as the control group, mild moxibustion was supplemented at Guānyuan (关元CV4), Qihai (气海CV6), Pishū (脾俞BL20) (bilateral) and Shenshū (肾俞BL23) (bilateral). The duration of treatment was 3 menstrual cycles in either group. Before treatment and on the 9th day of menstruation after 3-menstrual cycle treatment, the number of antral follicles and ovarian volume were detected by color Doppler ultrasound respectively. Before treatment and on day 2 to 4 of menstruation after 3-menstrual cycle treatment, the levels of serum estrogen (E2), follicle-stimulating hormone (FSH), interleukin-21 (IL-21) and vascular endothelial growth factor (VEGF) were determined separately and the therapeutic effect was evaluated in two groups separately. Results The effective rate was 93.94% in the observation group and was 72.73% in the control group (P 0.05). But in the observation group, the levels of serum IL-21 and VEGF after treatment changed apparently as compared with those before treatment (both P Conclusion The combined treatment of mild moxibustion with western medication achieves the definite therapeutic effect on POF and it increases the number of antral follicles and ovarian volume and regulates sex hormone level, which is probably related to the regulation of serum IL-21 and VEGF.
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
0211 other engineering and technologies
02 engineering and technology
Moxibustion
030226 pharmacology & pharmacy
Gastroenterology
Menstruation
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Sex hormone-binding globulin
Internal medicine
021105 building & construction
Medicine
biology
business.industry
Therapeutic effect
Antral follicle
medicine.disease
Premature ovarian failure
Vascular endothelial growth factor
Complementary and alternative medicine
chemistry
biology.protein
business
Hormone
Subjects
Details
- ISSN :
- 10035257
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- World Journal of Acupuncture - Moxibustion
- Accession number :
- edsair.doi...........fef11d18b2241a0aa4bc6772db15a903