A Novel Oral GyrB/ParE Dual Binding Inhibitor Effective against Multidrug-Resistant Neisseria gonorrhoeae and Other High-Threat Pathogens

Authors :: Steven Park
Riccardo Russo
Landon Westfall
Riju Shrestha
Matthew Zimmerman
Veronique Dartois
Natalia Kurepina
Barry Kreiswirth
Eric Singleton
Shao-Gang Li
Nisha Mittal
Yong-Mo Ahn
Joseph Bilotta
Kristie L. Connolly
Ann E. Jerse
Joel S. Freundlich
David S. Perlin
Source :: Antimicrobial Agents and Chemotherapy. 66
Publication Year :: 2022
Publisher :: American Society for Microbiology, 2022.
Abstract: Drug-resistant Neisseria gonorrhoeae is a serious global health concern. New drugs are needed that can overcome existing drug resistance and limit the development of new resistances.

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