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Thyroid Hormone Regulation of Specific mRNAS in the Developing Brain
- Source :
- Iodine and the Brain ISBN: 9781461280712
- Publication Year :
- 1989
- Publisher :
- Springer US, 1989.
-
Abstract
- Thyroid hormones, T3 and T4, have been shown to play significant but poorly understood roles in development and differentiation of rodent and human brain (1–7). In the human, disorders of maternal and fetal thyroid function include maternal and secondary fetal iodine deficiency, maternal hypothyroidism or hyperthyroidism, as well as disorders related to deficient fetal autonomous thyroid hormone secretion, i.e., goiter or sporadic congenital hypothyroidism. These disorders are identifiable causes of mental retardation (4, 8, 9, 10), cerebral palsy (11, 12), and other significant neurological abnormalities (5, 6, 11).
- Subjects :
- endocrine system
medicine.medical_specialty
Goiter
Thyroid hormone receptor
endocrine system diseases
business.industry
Thyroid
medicine.disease
Iodine deficiency
Congenital hypothyroidism
Thyroid hormone receptor beta
Endocrinology
medicine.anatomical_structure
Maternal hypothyroidism
Internal medicine
medicine
Thyroid function
business
Subjects
Details
- ISBN :
- 978-1-4612-8071-2
- ISBNs :
- 9781461280712
- Database :
- OpenAIRE
- Journal :
- Iodine and the Brain ISBN: 9781461280712
- Accession number :
- edsair.doi...........fca260472816cfddcf9e51e228865533