Back to Search Start Over

Ugi three-component coupling reaction for the synthesis of 2-(6-oxo-11-phenyl-7,8-dihydrobenzo[b]pyrrolo[1,2-d][1,4]diazocin-5(6H)-yl)-2-phenylacetamide derivatives

Authors :
P. Lakshmi Reddy
M. Lakshmi Devi
D. Ashok Kumar
R. Narender
B. V. Subba Reddy
T. Veera Reddy
Source :
Tetrahedron Letters. 55:657-661
Publication Year :
2014
Publisher :
Elsevier BV, 2014.

Abstract

A three-component, four center Ugi reaction of 3-(1-(2-aminophenyl)-5-phenyl-1H-pyrrol-2-yl)propanoic acid with aromatic aldehyde and t-butyl isocyanide has been achieved to produce a novel class of N-tert-butyl-2-(6-oxo-11-phenyl-7,8-dihydrobenzo[b]pyrrolo[1,2-d][1,4]diazacine-5(6H)-yl)-2-phenylacetamides in moderate to good yields.

Details

ISSN :
00404039
Volume :
55
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........fc7cd442b03719e368f782bfefb55fe4
Full Text :
https://doi.org/10.1016/j.tetlet.2013.11.106