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Ugi three-component coupling reaction for the synthesis of 2-(6-oxo-11-phenyl-7,8-dihydrobenzo[b]pyrrolo[1,2-d][1,4]diazocin-5(6H)-yl)-2-phenylacetamide derivatives
- Source :
- Tetrahedron Letters. 55:657-661
- Publication Year :
- 2014
- Publisher :
- Elsevier BV, 2014.
-
Abstract
- A three-component, four center Ugi reaction of 3-(1-(2-aminophenyl)-5-phenyl-1H-pyrrol-2-yl)propanoic acid with aromatic aldehyde and t-butyl isocyanide has been achieved to produce a novel class of N-tert-butyl-2-(6-oxo-11-phenyl-7,8-dihydrobenzo[b]pyrrolo[1,2-d][1,4]diazacine-5(6H)-yl)-2-phenylacetamides in moderate to good yields.
Details
- ISSN :
- 00404039
- Volume :
- 55
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters
- Accession number :
- edsair.doi...........fc7cd442b03719e368f782bfefb55fe4
- Full Text :
- https://doi.org/10.1016/j.tetlet.2013.11.106