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Therapeutic Delivery of miR-143 Targeting Tumor Metabolism in Poorly Differentiated Thyroid Cancer Xenografts and Efficacy Evaluation Using 18F-FDG MicroPET-CT
- Source :
- Human Gene Therapy. 30:882-892
- Publication Year :
- 2019
- Publisher :
- Mary Ann Liebert Inc, 2019.
-
Abstract
- Poorly differentiated thyroid carcinoma cells tend to be more aggressive and show enhanced glucose uptake which could be exploited for anti-cancer strategy. Previously, we identified hexokinase 2 (...
- Subjects :
- 0303 health sciences
business.industry
Poorly differentiated
Glucose uptake
Metabolism
medicine.disease
03 medical and health sciences
0302 clinical medicine
Poorly Differentiated Thyroid Carcinoma
030220 oncology & carcinogenesis
Genetics
medicine
Cancer research
Molecular Medicine
business
Molecular Biology
Thyroid cancer
030304 developmental biology
Subjects
Details
- ISSN :
- 15577422 and 10430342
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Human Gene Therapy
- Accession number :
- edsair.doi...........fc63fa3a3c436926a591011f2b19c8ac