Clinical feasibility and acceptability study of an online mindfulness and self-compassion integrated psychoeducation program for eczema in adults

ObjectiveAlthough mindfulness and self-compassion programs have been applied in clinical settings, no studies have reported their benefits for atopic dermatitis (AD). The aim of the study was to evaluate the feasibility and acceptability of an online group format of 8 weekly 90-minute sessions of a mindfulness and self-compassion program for adults with AD.ResultsIn this single-arm, open label pre-post comparison study design, 15 adults (10 women; mean age, 38.3 ± 8.98 years) completed the intervention and assessment. The primary outcome was disease-specific quality of life (QOL) (Dermatology Life Quality Index and Skindex-16) at the 20-week follow-up. The secondary outcomes were other self-reported questionnaires, and descriptive feedback of the program. Assessments were conducted at baseline, mid-treatment, post-intervention, and at follow-up. Overall, there were no significant improvements. However, of the four participants whose QOL was largely impacted due to AD, the scores improved significantly, with minimal clinically important difference or greater change. All participants were satisfied with the program. This program could benefit adults with AD by improving QOL. Randomized controlled trials are warranted to elucidate the efficacy of the program. This study has been registered at the UMIN Clinical Trials Registry (ID: UMIN000030484).