Impact of sex on management and survival in aortic stenosis

Background Increasing attention has been paid to differences between the sexes in recent studies, but only a few have focused on such differences in aortic stenosis (AS). Purpose We sought to evaluate the differences between genders in AS outcomes and management. Methods We included 2429 patients (51.5% men; 49.5% women) with severe AS. Median follow-up was 42.0 (21–78) months. Results Women were older (p Conclusion Women with severe AS present at a more advance stage of the disease, at older ages with more symptoms, and incur higher mortality than men. This excess mortality is related to a combination of late diagnosis and a less frequent and later referral for AVR than in men. This justifies appropriate measures to improve the situation and to ensure that both sexes receive equivalent care. Figure 1. (A) Survival curves. (B) Surgery incidence. Funding Acknowledgement Type of funding source: None