The AcrySof Toric Intraocular Lens in Subjects with Cataracts and Corneal Astigmatism

Purpose To compare the AcrySof Toric intraocular lens (IOL) and an AcrySof spherical control IOL and to investigate rotational stability of the AcrySof Toric IOL (Alcon Laboratories, Inc., Fort Worth, TX) in subjects with cataracts and preexisting corneal astigmatism. Design Randomized, subject-masked, parallel-group, multicenter, 1-year study. Participants We included 517 subjects (Toric IOL, n=256; control IOL, n=261). Methods Unilateral implantation of an AcrySof Toric or AcrySof spherical control IOL (spherical powers, 12.00–25.00 diopters [D]; cylinder powers 1.50, 2.25, or 3.00 D for corneal astigmatism correction of 0.75 to Main Outcome Measures Visual acuity outcomes, IOL position, patient-reported spectacle use, and safety. Results One year postoperatively, best spectacle-corrected distance visual acuity of ≥20/20 was 77.7% (Toric IOL) versus 69.2% (control IOL). Uncorrected distance visual acuity of 20/20 or better was 40.7% (Toric IOL) versus 19.4% (control IOL; P P P Conclusions Favorable efficacy, rotational stability, distance vision spectacle freedom, and safety results support the use of the AcrySof Toric IOL for patients with cataracts and corneal astigmatism. Financial Disclosure(s) Proprietary or commercial disclosure may be found after the references.