Social Determinant of Health and Survival on Brazilian Patients With Glioblastoma: An Analysis of a Large Populational Database

Background: The majority of patients diagnosed with glioblastoma develop recurrent disease resulting in poor prognoses. The current study aimed to determine the survival rates of patients diagnosed with glioblastoma in Brazil accounting for the influence of age, treatment modalities, public and private practices, and educational level using a population-based national database. Methods" Patients diagnosed with glioblastoma from 1999-2020 were identified from The Fundacao Oncocentro de Sao Paulo database to create a retrospective cohort. Patients were described according to age, education level treatment modalities and medical practice. In a Cox proportional hazards model, controlled for confounding factors for overall survival, the hazard ratio and 95% CI of overall survival in adults with and without glioblastoma was evaluated. Results: A total of 4,511 patients were included. The median lengths of survival for patients treated in the public and private settings were 8 and 17 months (p