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Human liver degradation of 5-fluorouracil: endogenous uracil may result in phenoconversion of dihydropyrimidine dehydrogenase activity

Authors :
Kathryn E Burns
Brent C. McGillivray
Malcolm D. Tingle
Liam Andrews
Nuala A. Helsby
Source :
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO4-10
Publication Year :
2018
Publisher :
Japanese Pharmacological Society, 2018.

Subjects

Subjects :
chemistry.chemical_compound
Biochemistry
Human liver
Fluorouracil
Chemistry
Applied Mathematics
General Mathematics
medicine
Degradation (geology)
Endogeny
Uracil
Dihydropyrimidine dehydrogenase activity
medicine.drug

Details

ISSN :
24354953
Database :
OpenAIRE
Journal :
Proceedings for Annual Meeting of The Japanese Pharmacological Society
Accession number :
edsair.doi...........fb0a882ad9950c41cf51007b7bb9f2ca
Full Text :
https://doi.org/10.1254/jpssuppl.wcp2018.0_po4-10-1
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