Terlipressin Induced Skin Ischemia: A Case Report

Terlipressin is a synthetic vasopressin analogue used in the treatment of cirrhotic patients with variceal bleeding and hepatorenal syndrome. Side effects associated with terlipressin are usually mild but some rare serious complications can also be seen. Terlipressin induced skin ischemia is one such serious complication. We report a case of 57-year-old lady, a case of chronic alcoholic liver disease presented with variceal bleeding. Patient was given bolus injection terlipressin every 4 hour and patient developed skin ischemia within 48 hours of terlipressin administration. Skin ischemic changes showed marked improvement after stoppage of terlipressin. Treating clinicians should be more vigilant about this rare adverse effect of terlipressin. Early recognition and treatment of the ischemic skin complication gives a better outcome. How to cite this article: Kumar N, Bohania N, Kumar S. Terlipressin Induced Skin Ischemia: A Case Report. J Adv Res Med 2019; 6(4): 10-12. DOI: https://doi.org/10.24321/2349.7181.201918