A survey of the domestic epidemiological characteristics and clinical manifestations of pertussis

Purpose: This report describes the results of a survey of the characteristics of pertussis in children from a single institution and com pares it to data from the Korea Centers of Disease Control (KCDC). Methods: We retrospectively evaluated the medical records of 17 and 6 patients diagnosed with pertussis and parapertussis, re spectively, at Soonchunhyang University Bucheon Hospital from January 2005 to January 2017. Results: Of the 17 patients with pertussis, 9 were under 1 year of age (52.9%), 3 were aged between 1 and 10 years (17.6%), and 5 were over 10 years of age (29.4%). Seven patients (41.2%) had never received diphtheria-tetanus-acellular pertussis vaccines, of which 5 were infants below 2 months of age and 2 were 10 years old and lived in China. Four patients showed the initial symptoms of cough in China. The sources of infection were the parents (2 cases) and the siblings (8 cases). All patients showed prolonged se vere cough and the average duration of cough was 26 days. Severe symptoms, including dyspnea, cyanosis, apnea, and seizures, were observed in the children under 2 months of age. According to the recent 10-year KCDC data, the highest rate of pertussis diag nosis was noted in infants (47.8%), followed by adolescents (18.7%). Six patients with parapertussis also presented with prolonged severe cough without any other severe symptoms. Lymphocytosis was not found, unlike the patients with pertussis. Conclusion: The possibility of pertussis and parapertussis should be considered among patients with prolonged severe cough, es pecially in infants and adolescents. (Allergy Asthma Respir Dis 2018;6:54-61)