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ChemInform Abstract: Intermolecular Dipolar Cycloaddition Reactions of 5H,7H-Thiazolo[3,4-c]oxazol-4-ium-1-olates
- Source :
- ChemInform. 31
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- (5R)-3-Methyl-5-phenyl-5H,7H-thiazolo[3,4-c]oxazol-4-ium-1-olate was generated in the presence of a range of dipolarophiles. The intermolecular 1,3-dipolar cycloaddition of this mesoionic species led to the synthesis of chiral 1H-pyrrolo[1,2-c]thiazole derivatives 7a, 7b, 8, 14, 18, 19 and 20. In the reaction with methyl and ethyl vinyl ketone, spiro compounds 9 and 15 were also obtained. The structure of compound 15 was determined by X-ray crystallography.
Details
- ISSN :
- 15222667 and 09317597
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........f95222061acf43c5dbac383adc1f46f6