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ChemInform Abstract: Rapid Synthesis of Isoquinolinones by Intramolecular Coupling of Amides and Ketones
- Source :
- ChemInform. 46
- Publication Year :
- 2015
- Publisher :
- Wiley, 2015.
-
Abstract
- Amides and ketones were intramolecularly coupled in the presence of KOt-Bu/DMF. The reaction provided good yields of a variety of isoquinolinones. A reaction mechanism of radical addition and subsequent E2-elimination is proposed.
Details
- ISSN :
- 09317597
- Volume :
- 46
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........f86298eaf815993d123cd1f32878b8a6
- Full Text :
- https://doi.org/10.1002/chin.201521178