IMMUNOGLOBULIN G4–RELATED OPHTHALMIC DISEASE MIMICKING INTRAOCULAR LYMPHOMA: A CASE REPORT

Purpose To describe a case of IgG4-related choroiditis mimicking intraocular lymphoma. Methods The patient underwent a complete ophthalmological evaluation including multimodal imaging, with structural optical coherence tomography (OCT), fluorescein angiography (FA), indocyanine green angiography (ICGA), Ultra-Wide Field color and autofluorescent fundus photographies to assess the ocular involvement. Results Patient BCVA was of 20/25 in the right eye and 20/20 in the left eye. Fundus appearance showed abnormal yellowish choroidal lesions and moderate vitritis in both eyes . FA was within normal limits while ICGA showed areas of choroiditis in both eyes and structural OCT scans disclosed retinal small roundish lesions in the corresponding regions. Laboratory exams and lymph node biopsy led to the final diagnosis of IgG4-related disease. Conclusions We describe a case of IgG4-related choroiditis mimicking intraocular lymphoma. The proper use of multimodal imaging associated with laboratory investigations was useful to reach the correct diagnosis.