Stabilized next-generation recombinant human acid alpha-glucosidase ATB200 clears accumulated glycogen and reverses cellular dysfunction to increase functional muscle strength in a mouse model of Pompe disease

Authors :: Adriane Schilling
Do Hung
Richie Khanna
Yi Lun
Anju Nair
Michelle Frascella
Rebecca Soska
Cecilia Della Valle
Kenneth J. Valenzano
Su Xu
Anadina Garcia
Jessie Feng
Russell Gotschall
Source :: Molecular Genetics and Metabolism. 120:S42
Publication Year :: 2017
Publisher :: Elsevier BV, 2017.

Subjects :: chemistry.chemical_compound
Endocrinology
Biochemistry
Glycogen
chemistry
Endocrinology, Diabetes and Metabolism
Genetics
Muscle strength
Recombinant human acid alpha-glucosidase
Disease
Biology
Molecular Biology

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