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First Report of Three Major Oncogenic Viruses: Human Papillomavirus, Epstein-Barr Virus And Merkel Cell Polyomavirus in Penile Cancer

First Report of Three Major Oncogenic Viruses: Human Papillomavirus, Epstein-Barr Virus And Merkel Cell Polyomavirus in Penile Cancer

Authors :
Rafael Brandão Varella
Cavalcanti Smb
Guimarães Maam
da Rocha Wm
Fernanda Nahoum Carestiato
Camila Freze Baez
Larissa Alves Afonso
Source :
Journal of Infectious Diseases & Therapy.
Publication Year :
2015
Publisher :
OMICS Publishing Group, 2015.

Abstract

We report here in first hand a case of triple infection caused by oncogenic viruses: HPV16, EBV-2 and MCPyV, in a squamous cell carcinoma of penis with an unfavorable outcome. Although reports on multiple viral infections in tumors are increasing, we do not know whether they are simply co-detected in the tissue or playing a synergistic role in the tumorigenesis. Studies addressing a putative co-stimulatory effect among these agents are needed in order to improve our comprehension of cell transformation.

Details

ISSN :
23320877
Database :
OpenAIRE
Journal :
Journal of Infectious Diseases & Therapy
Accession number :
edsair.doi...........f706c0510b344ccf272d87a01341fec8
Full Text :
https://doi.org/10.4172/2332-0877.1000233