Development of Non-peptidic Farnesyltransferase Inhibitors based on the Ca1a2of Ras-CaaX

Though it is not clear at this point whether FTase inhibition is directly related to the anticancer activity or not, development of FTI is still attractive to find a cure for cancer as well as to find the real target of these compounds. Furthermore, FTIs were also found to have great potential for treatment of malaria, African sleeping disease, and hepatitis