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Stereoselective aldol condensation of boron enolates to trans α,β-epoxy aldehydes
- Source :
- Tetrahedron Letters. 43:4737-4740
- Publication Year :
- 2002
- Publisher :
- Elsevier BV, 2002.
-
Abstract
- A study on the addition of boron enolates of methyl ketones to trans α,β-epoxy aldehydes is reported. The reaction proceeds with an excellent anti stereoselectivity, consistent with the Felkin–Ahn model, toward the synthesis of hydroxylated compounds with defined stereochemistry.
Details
- ISSN :
- 00404039
- Volume :
- 43
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters
- Accession number :
- edsair.doi...........f5ecaa996c1e2fa8f803fd4f76c21b94