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Bactericidal efficacy of nanopatterned surface tuned by topography
- Source :
- Journal of Applied Physics. 128:064701
- Publication Year :
- 2020
- Publisher :
- AIP Publishing, 2020.
-
Abstract
- Due to the exciting physical mechano-bactericidal approach developed in recent years using nanopatterned surfaces with its potential applications in biomedical engineering, now it becomes crucially important to fabricate optimal surface structures so as to achieve the best bactericidal ability. In this paper, the bactericidal efficacy of the cylindrical nanopillar-patterned surface and the sinusoidal nanopillar-patterned surface is presented via minimizing total free energy for a bacterial cell adhered on these two kinds of surfaces. Our theoretical analyses show that the adhesion depth at equilibrium along the nanopillar shafts and the corresponding stretching degree is related to the the nanopillar density and nanopillar radius. The bactericidal efficacy on the nanopillar-patterned surface is determined by the combination of nanopillar density and naopillar radius, which is also supported by the phase diagrams obtained, showing that at large internanopillar spacing and nanopillar radius, the sinusoidal nanopillar-patterned surface is more advantageous in bactericidal efficacy, while in small interspacing and nanopillar radius, the cylindrical nanopillar-patterned surface structure is more powerful. The conclusions obtained in this paper unveil how the mechano-bactericidal effect is achieved by tuning the topography of the nanopatterned surface, a technique helpful to the optimal design and fabrication of bio-mimicking nanotextured surfaces.
- Subjects :
- 010302 applied physics
Surface (mathematics)
Materials science
Fabrication
business.industry
General Physics and Astronomy
02 engineering and technology
Adhesion
Radius
021001 nanoscience & nanotechnology
01 natural sciences
0103 physical sciences
Optoelectronics
Surface structure
Nanotextured Surfaces
0210 nano-technology
business
Phase diagram
Nanopillar
Subjects
Details
- ISSN :
- 10897550 and 00218979
- Volume :
- 128
- Database :
- OpenAIRE
- Journal :
- Journal of Applied Physics
- Accession number :
- edsair.doi...........f5a1515cba5f77eaeea67d9f21b996f1