The Change of Electrical Properties of Blood Corpuscles under in vitro Mechanical Stress

Changes in the electrical properties of blood corpuscles that are experiencing mechanical stress modeled in vitro have been studied. An increase in the concentration of ATP molecules in the intercellular space in response to the mechanical effect of moving plasma layers both in the blood of healthy people and patients with acute lymphoblastic leukemia is demonstrated. The surface potential of red blood cells and platelets becomes more positive both in the blood of healthy people and in leukemia patients. In contrast, the negative charge of lymphocytes in healthy people decreases in response to mechanical stress but increases in the blood of patients with acute lymphoblastic leukemia.