Synthesis and Tuberculostatic Activity of Some 1,2,4-Triazines

Authors :: Marionella A. Kravchenko
A. E. Ivanova
Evgeny V. Shchegolkov
Olga G. Khudina
E. V. Sadchikova
Viktor I. Saloutin
Ya. V. Burgart
Source :: Pharmaceutical Chemistry Journal. 48:383-386
Publication Year :: 2014
Publisher :: Springer Science and Business Media LLC, 2014.
Abstract: The antituberculosis activity of dihydrotriazolo[5,1-c][1,2,4]triazines, dihydropyrazolo[5,1-c][1,2,4]triazines, dihydroimidazolo[5,1-c][1,2,4]triazines, and dihydrotetrazolo[5,1-c][1,2,4]triazines was studied. A synthetic method for convenient synthons, 3-amino-1,2,4-triazines, was proposed. Their tuberculostatic activity was investigated.