Antibacterial Activity and Synergism of the Hybrid Antimicrobial Peptide, CAMA-syn

Authors :: Jin-Kyoung Kim
Yangmee Kim
Soyoung Shin
Ki-Woong Jeong
Source :: Bulletin of the Korean Chemical Society. 30:1839-1844
Publication Year :: 2009
Publisher :: Korean Chemical Society, 2009.
Abstract: A 20-residue hybrid peptide CA(1-8)-MA(1-12) (CAMA) incorporating residues 1-8 of cecropin A (CA) and residues 1-12 of magainin 2 (MA) has high antimicrobial activity without toxicity. To investigate the effects of the total positive charges of CAMA on the antibacterial activity and toxicity, a hybrid peptide analogue (CAMA-syn) was designed with substitutions of Ile

Subjects :: chemistry.chemical_classification
Cecropin A
Chemistry
medicine.drug_class
Flavonoid
Antibiotics
Magainin
Peptide
General Chemistry
Antimicrobial
chemistry.chemical_compound
Biochemistry
Toxicity
medicine
Antibacterial activity

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