Karzinomassoziierte Retinopathie (CAR) bei neuroendokrinem Uteruskarzinom

A 75-year-old female patient presented with bilateral progressive loss of vision. Best corrected visual acuity (BCVA) was hand movements in the right eye and 1/50 in the left eye. The spectral domain optical coherence tomography (SD-OCT) showed thinning of the outer retina suspected to be due to autoimmune retinopathy. A neuroendocrine carcinoma of the uterus was diagnosed during tumor screening. Under systemic therapy with corticosteroids the visual acuity improved to 20/200 in the right eye and 20/80 in the left eye. Cancer-associated retinopathy (CAR) is a paraneoplastic autoimmune retinopathy.