An Artificial Intelligence-Based Smart System for Early Glaucoma Recognition Using OCT Images

Glaucoma is a progressive and constant eye disease that leads to a deficiency of peripheral vision and, at last, leads to irrevocable loss of vision. Detection and identification of glaucoma are essential for earlier treatment and to reduce vision loss. This motivates us to present a study on intelligent diagnosis system based on machine learning algorithm(s) for glaucoma identification using three-dimensional optical coherence tomography (OCT) data. This experimental work is attempted on 70 glaucomatous and 70 healthy eyes from combination of public (Mendeley) dataset and private dataset. Forty-five vital features were extracted using two approaches from the OCT images. K-nearest neighbor (KNN), linear discriminant analysis (LDA), decision tree, random forest, support vector machine (SVM) were applied for the categorization of OCT images among the glaucomatous and non-glaucomatous class. The largest AUC is achieved by KNN (0.97). The accuracy is obtained on fivefold cross-validation techniques. This study will facilitate to reach high standards in glaucoma diagnosis.