Electrospun scaffolds for cardiac tissue engineering

Cardiovascular diseases are the major cause of human mortality worldwide. Therefore, cardiac tissue engineering has emerged as a therapeutic approach to develop bioengineered constructs that can be potentially implanted in order to provide support to the damaged cardiac tissue and restore heart function. One of the promising strategies in cardiac tissue engineering relies on nanostructured scaffolds supplemented with biomolecules mimicking the native ECM architecturally and biochemically to promote cell functions and cardiac tissue formation. Therefore, electrospun nanofibers have found various applications as the cardiac patches, drug delivery systems, heart valve prosthesis, etc. This chapter aims to review the applications of the electrospun scaffolds in cardiac tissue engineering.