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Expression of leptin receptor in renal tubules is sparse but implicated in leptin-dependent kidney gene expression and function

Authors :
Young Chul Kim
Hadi Fattah
Yiling Fu
Josselin Nespoux
Volker Vallon
Source :
American Journal of Physiology-Renal Physiology. 324:F544-F557
Publication Year :
2023
Publisher :
American Physiological Society, 2023.

Abstract

This study provides new insights into kidney gene expression of leptin receptor splice variants, leptin-sensitive kidney gene expression, and the role of the leptin receptor in renal tubular cells for the response to diet-induced hyperleptinemia and obesity including albuminuria.

Subjects

Subjects :
Physiology

Details

ISSN :
15221466 and 1931857X
Volume :
324
Database :
OpenAIRE
Journal :
American Journal of Physiology-Renal Physiology
Accession number :
edsair.doi...........f350034fc15969ad35e036d573f75d52