Efficacy of various topical agents in chronic plaque type psoriasis

Psoriasis is a common, chronic, inflammatory, hyper-proliferative disease of the skin and joints characterized by erythematous plaques covered with silvery white scales. There are many topical and systemic modalities for its treatment. Out of all topical treatment, ammonium lactate has been studied very little for its role in psoriasis vulgaris. As there is paucity of literature on ammonium lactate as monotherapy and its combination with other topical agents, this study has been undertaken and it was found that combination therapy is effective, well tolerated with minimal side effects and better compliance was seen. Ammonium lactate can also be considered as one of the topical option as a monotherapy and also as a maintenance therapy. Keywords: Psoriasis, Ammonium lactate, Topical, Calcipotriol.