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A Direct Synthesis of 3,5‐Dibromo‐O‐methyl‐<scp>L</scp>‐tyrosine
- Source :
- Synthetic Communications. 34:547-555
- Publication Year :
- 2004
- Publisher :
- Informa UK Limited, 2004.
-
Abstract
- A simple and efficient synthesis of 3,5‐dibromo‐O‐methyl‐L‐tyrosine is described by direct bromination of commercial O‐methyl‐L‐tyrosine with bromine in aqueous hydrochloric acid. MO calculations are presented to explain a difference in the degree of substitution of O‐methyl‐L‐tyrosine in different solvents.
Details
- ISSN :
- 15322432 and 00397911
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- Synthetic Communications
- Accession number :
- edsair.doi...........f1ecb260bc7377af8954655ed496419b
- Full Text :
- https://doi.org/10.1081/scc-120027296