An engineered β-galactosidase with improved stability and cross-correction for the potential treatment of GM1 Gangliosidosis via AAV gene therapy

Authors :: Charu Reddy
Ouma Onguka
Jacob Artz
Christopher Schmitt
Adam Grossman
Swetha Santosh
Oluwayomi Akinkugbe
Victoria Wong
Kahsay Gebretsadik
Faezeh Sedighi
Jinyan Tang
Elizabeth Del Greco
Grace S. Lee
Nikki Kruse
Chinping Chng
Da Duan
William C. Hallows
Joseph C. Chen
Hassibullah Akeefe
Adam P. Silverman
Gjalt Huisman
Source :: Molecular Genetics and Metabolism. 138:107285
Publication Year :: 2023
Publisher :: Elsevier BV, 2023.

Subjects :: Endocrinology
Endocrinology, Diabetes and Metabolism
Genetics
Molecular Biology
Biochemistry

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