Electrolytic Partial Fluorination of Organic Compounds. 66. Anodic Fluorination of (Thiazol-2-yl)acetonitriles

Electrochemical partial fluorination of (4-arylthiazol-2-yl)acetonitriles was carried out to afford the corresponding (4-aryl-5-fluoro-5H-thiazol-2-ylidene)acetonitriles as main products in addition to (4-aryl-5-fluorothiazol-2-yl)acetonitriles and (4-arylthiazol-2-yl)fluoroacetonitriles. AMI calculations were conducted to compare the stability of the fluorinated products.