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Rebound thymic hyperplasia after liver transplantation for a child with biliary atresia; a case report
- Source :
- Pediatric Transplantation. 22:e13251
- Publication Year :
- 2018
- Publisher :
- Wiley, 2018.
-
Abstract
- The thymus gland possesses the ability to regrow in children leading to a newly developed anterior mediastinal mass. This condition may represent a rebound phenomenon during recovery from a stressful event such as post-chemotherapy and hence was described as RTH. RTH after LT has not been well documented. We are reporting an infant with BA who underwent LT and presented with a symptomless anterior mediastinal mass, detected on follow-up imaging 6 months thereafter. Surgical partial excision was performed to rule out other differential diagnoses of a solid mass in the anterior mediastinum of an infant particularly lymphoma-that may arise as post-transplant lymphoproliferative disorder-and teratoma, as well as the other aggressive lesions such as thymoma and thymic carcinoma. The final pathological analysis revealed true thymic hyperplasia, consistent with RTH. The diagnosis of RTH should be considered for a child presenting by anterior mediastinal mass after LT.
- Subjects :
- Transplantation
Pathology
medicine.medical_specialty
Thymoma
business.industry
medicine.medical_treatment
digestive, oral, and skin physiology
030230 surgery
Hyperplasia
Liver transplantation
medicine.disease
030218 nuclear medicine & medical imaging
True Thymic Hyperplasia
03 medical and health sciences
0302 clinical medicine
Biliary atresia
Pediatrics, Perinatology and Child Health
medicine
Teratoma
business
Thymic carcinoma
Subjects
Details
- ISSN :
- 13973142
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Pediatric Transplantation
- Accession number :
- edsair.doi...........f161381a7f45609540b7f6cff0450c3b