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Cas9 and the importance of asymmetry
- Source :
- Nature Methods. 13:287-287
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- Short single-stranded DNA donors that asymmetrically span the Cas9 cut site show high efficiency in homology-directed editing.
- Subjects :
- 0301 basic medicine
Genetics
Cas9
media_common.quotation_subject
Genomics
Cell Biology
Computational biology
Biology
Span (engineering)
Biochemistry
Asymmetry
03 medical and health sciences
chemistry.chemical_compound
030104 developmental biology
chemistry
Homologous recombination
Molecular Biology
DNA
Biotechnology
media_common
Subjects
Details
- ISSN :
- 15487105 and 15487091
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Nature Methods
- Accession number :
- edsair.doi...........f11f3535204f12a394e4c8ac4b9cd605
- Full Text :
- https://doi.org/10.1038/nmeth.3826