Su1068 Do Patients Report Symptoms When They Occur? Fundamental Consequences for Interpretation of Ambulatory Reflux Monitoring

Introduction: Gastroesophageal reflux (GER) causes esophageal and extra-esophageal symptoms. Frequent extra-esophageal symptoms are cough, laryngospasm, laryngitis and asthma. Microand macro-aspiration are hypothesized pathophysiologic mechanisms. Aim: to compare the results obtained with two techniques that can measure reflux in the hypo-pharynx. Methods: The "Restech technique" evaluate the pH at the level of the hypo-pharynx through a probe with a pH-antimony sensor which is placed behind the soft palate. Mutichannel intraluminal impedance/pH-monitoring (MII/pH) records the passage gas and liquid reflux, and the pH of the latter, through a probe with 6 impedance sensors and 2 pH antimony sensors (the lower at 3 cm above the LES and the high at the level of hypo-pharynx). Ten adults patients (age 46.33 ± 9.86yrs; range 33.9-66.11) presenting with chronic coughing underwent simultaneous a Restech and MII/pH recording. A time-interval of 2 minutes was allowed between Restech and MII/pH to be considered simultaneous episodes. The results were statistically tested with the Chi-square test; a p value