Magnetic resonance imaging of two suspected cases of global brain ischemia

Objective: To describe the clinical findings and magnetic resonance imaging (MRI) characteristics of two animals with suspected global brain ischemia (GBI). Series summary: Two brachycephalic animals (Persian cat and Boston terrier) presented for altered mentation, blindness, ataxia, and seizures after being anesthetized. Common to both anesthetic protocols was ketamine. Clinically, the neurological deficits developed rapidly and did not progress after the initial 24 hours. MRI findings were most consistent with GBI. MRI, including pre- and post-T1 weighted, T2 weighted, and fluid-attenuated inversion recovery (FLAIR) studies, was used to image these animals. Abnormalities were seen post-T1, T2, and FLAIR. Both animals improved neurologically with supportive care over several weeks, but both remained blind. New information: The use of MRI for diagnosing GBI.