ChemInform Abstract: A Novel Method for the Preparation of Macrolides from ω- Hydroxycarboxylic Acids

Authors :: Teruaki Mukaiyama
Isamu Shiina
Source :: ChemInform. 25
Publication Year :: 2010
Publisher :: Wiley, 2010.
Abstract: An efficient method for the synthesis of macrolides directly from ω-hydroxycarboxylic acids is established by using 4-(trifluoromethyl)benzoic anhydride and a catalytic amount of active titanium(IV) salts together with chlorotrimethylsilane under mild conditions.

Subjects :: chemistry.chemical_compound
Trifluoromethyl
chemistry
Organic chemistry
chemistry.chemical_element
General Medicine
Benzoic anhydride
Catalysis
Titanium

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