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Alkylation stereochemistry of camphor derivatives of glycinates. Double chiral induction with secondary halides

Authors :
Randy K. Leavitt
John M. McIntosh
Source :
Tetrahedron Letters. 27:3839-3842
Publication Year :
1986
Publisher :
Elsevier BV, 1986.

Abstract

Alkylation of the D-camphor imine of tert -butyl glycinate with secondary allylic and benzylic halides affords products which have high stereochemical purity, particularly at the halogen displacement site.

Details

ISSN :
00404039
Volume :
27
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........ee223858dd6c9b03c3e4c19f3513f6b3
Full Text :
https://doi.org/10.1016/s0040-4039(00)83893-9