Rebubbling of DMEK Grafts

Although DMEK offers speedier recovery, improved visual outcomes, and lower rejection risk compared to DSAEK, the trade-off is an incrementally higher rate of rebubbling. Unlike DSAEK grafts, DMEK tissue rarely displays complete graft separation or severe decentration, which is why injection of an air bubble alone – without any further surgical manipulation – is enough to eliminate fluid from the graft-host interface and achieve complete graft attachment.