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Weapons of Mutational Destruction

Authors :
Vineet N. KewalRamani
John M. Coffin
Source :
Science. 301:923-925
Publication Year :
2003
Publisher :
American Association for the Advancement of Science (AAAS), 2003.

Abstract

The viral accessory protein Vif is required for the production of infectious virions by cells that do not normally permit viral replication to take place. In their Perspective, KewalRamani and Coffin discuss an exciting cluster of recent papers that identify a new viral mutagenic factor called APOBEC3G, which counteracts Vif9s ability to enable viral replication in nonpermissive cells.

Details

ISSN :
10959203 and 00368075
Volume :
301
Database :
OpenAIRE
Journal :
Science
Accession number :
edsair.doi...........ed47d48e4bf0e4199fff28b099a56695