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Studies on regioselective hydrogenation of thebaine and its conversion to hydrocodone

Authors :
Hannes Leisch
D. Phillip Cox
Robert J. Carroll
Tomas Hudlicky
Source :
Tetrahedron Letters. 48:3979-3981
Publication Year :
2007
Publisher :
Elsevier BV, 2007.

Abstract

Thebaine was subjected to catalytic hydrogenation under a variety of conditions in order to determine the regioselectivity for C-6/C-7 versus C-8/C-14 olefin saturation.

Details

ISSN :
00404039
Volume :
48
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........ed3791022fa7ffe89008d31686e602bc
Full Text :
https://doi.org/10.1016/j.tetlet.2007.04.051