Hospital based study on demographic profile and clinical spectrum on hereditary muscle disorder

Background: Myopathies are disorders in which a primary functional or structural impairment of skeletal muscle. In general, Muscle disorders are classified into hereditary and acquired disorders. The approach to a patient with a suspected muscle disease is to determine the correct site of the lesion from history and physical examination. This will help to decide on management and prognostication issues. We undertook this study of hereditary muscle disorders to identify the demographic profile and clinical spectrum of hereditary muscle disorders. Aims and Objectives: To study the demographic profile of patients with hereditary muscle disorders and to study the clinical spectrum of hereditary muscle disorders. Methods and Materials: A cross sectional study was conducted on Institute of Neurology, Madras Medical College, Chennai during the period of July 2018 to February 2019 (8 months), among 44 patients (Males-32, Females-12), with clinical features suggestive of hereditary muscle disorders, with certain exclusion criteria’s. Clinical evaluation was done by detailed history taking followed by general and CNS examination, along with motor system examination. All the data were tabulated in Microsoft XL sheet, followed by analysis using SPSS software (version 20.0).