DNA computing for a dominating set problem based on sticker models

Purpose – The bottleneck of current DNA computing paradigms based on brute‐force search strategy is that initial solution space grows exponentially with problem size, thus only trivial instances of NP‐complete problem can be solved. The purpose of this paper is to present a novel molecular program based on sticker models for solving dominating set problems.Design/methodology/approach – The authors do not synthesize the initial solution pool containing every possible candidate solution as previously reported algorithm. Instead, solutions DNA molecules to the problem of interest are constructed during the course of computation.Findings – It is shown that “exponential explosions” inherent in current DNA computing paradigms may be overcome in this way.Originality/value – The paper proposes an error‐resistant DNA algorithm based on sticker model for solving minimum dominating problems.