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Segmentale Aganglionose des Dünndarms - Mythos oder Wirklichkeit? (Eine Falldarstellung)
- Source :
- European Journal of Pediatric Surgery. 43:424-426
- Publication Year :
- 1988
- Publisher :
- Georg Thieme Verlag KG, 1988.
-
Abstract
- Reports on zonal aganglionosis of the bowel are very rare and the few cases reported concern colon and rectum. We present a case of segmental aganglionosis of the jejunum in a 2-months-old boy. He had to be operated upon twice because of an ileus of the short bowel. At the second operation, a 10 cm long narrow segment of the jejunum was resected. The histological examination revealed a segmental aganglionosis of the plexus myentericus. Possible causes of this rare zonal aganglionosis could be: 1. Local damage of the plexus myentericus through anoxia. 2. Primary abnormity in the gastrointestinal anlage. 3. An intrauterine inflammation. 4. A double migration and development gradient of the precursors of the neuroblasts, from each end to the middle of the gut. A defect in the microenvironment of the enteric neurons would result in their failure in differentiation. This possible explanation would challenge the accepted theory of pathogenesis of colonic aganglionosis.
- Subjects :
- medicine.medical_specialty
Ileus
business.industry
Rectum
Anatomy
medicine.disease
Gastroenterology
digestive system diseases
Plexus myentericus
Short bowel
Jejunum
medicine.anatomical_structure
Internal medicine
Pediatrics, Perinatology and Child Health
medicine
Jejunal Stenosis
Surgery
business
Colonic Aganglionosis
Histological examination
Subjects
Details
- ISSN :
- 1439359X and 09397248
- Volume :
- 43
- Database :
- OpenAIRE
- Journal :
- European Journal of Pediatric Surgery
- Accession number :
- edsair.doi...........eca07b48dc83213ec5484ce3d184b6d8