Alkaloids from seeds of Lupinus varius and L. hartwegii

A new lupin alkaloid, (−)-13 β -hydroxymultiflorine, was isolated from an ethanol extract of the seeds of Lupinus varius , together with 13 known lupin alkaloids. In addition, two new lupin alkaloids, (+)-2 β -hydroxyaphylline and (+)-13 α -hydroxyaphyllidine, were isolated from seeds of L. hartwegii , together with another 11 known lupin alkaloids. The identification of all compounds was established by spectral analysis.