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Panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma

Authors :
Christine McCluskey
Andrew D. Norden
Tracy T. Batchelor
Patrick Y. Wen
Lakshmi Nayak
David Schiff
Rameen Beroukhim
Jan Drappatz
Sarah C. Gaffey
Kelly Hempfling
Andrew S. Chi
Sean Grimm
Jeffrey Raizer
Mikael L. Rinne
Katrina H. Smith
Eudocia Q. Lee
David A. Reardon
Alona Muzikansky
Brendan Wrigley
Source :
Journal of Clinical Oncology. 32:2020-2020
Publication Year :
2014
Publisher :
American Society of Clinical Oncology (ASCO), 2014.

Abstract

2020 Background: Bevacizumab is frequently used to treat recurrent high-grade gliomas, but responses are generally not durable. Panobinostat is a histone deacetylase inhibitor with anti-neoplastic ...

Details

ISSN :
15277755 and 0732183X
Volume :
32
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........ebd59b4b54e857ece0d16875d8442842
Full Text :
https://doi.org/10.1200/jco.2014.32.15_suppl.2020