Structural Details of an Allosteric Mechanism for Bimodal Anesthetic Modulation of Pentameric Ligand-Gated Ion Channels

Authors :: Stephanie A. Heusser
Zaineb Fourati
Reinis R. Ruza
Haidai Hu
Erik Lindahl
Rebecca J. Howard
Marc Delarue
Ludovic Sauguet
Source :: Biophysical Journal. 114:204a
Publication Year :: 2018
Publisher :: Elsevier BV, 2018.
Abstract: Structural Details of an Allosteric Mechanism for Bimodal Anesthetic Modulation of Pentameric Ligand-Gated Ion Channels

Subjects :: Chemistry
Modulation
Mechanism (biology)
Allosteric regulation
Anesthetic
Biophysics
medicine
Ligand-gated ion channel
lipids (amino acids, peptides, and proteins)
Ion channel
medicine.drug

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