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A study to explore the correlation of trough level concentration and ABCB1, OCT1, ABCG2 genetic polymorphisms with imatinib mesylate induced thrombocytopenia in chronic myeloid leukemia patients
- Source :
- Journal of Clinical Oncology. 33:e13564-e13564
- Publication Year :
- 2015
- Publisher :
- American Society of Clinical Oncology (ASCO), 2015.
-
Abstract
- e13564 Background: Imatinib mesylate is presently the first line treatment for chronic myeloid leukemia (CML). Therapeutic drug monitoring (TDM) and pharmacogenetic screening is warranted for bette...
- Subjects :
- Oncology
Cancer Research
medicine.medical_specialty
Abcg2
biology
medicine.diagnostic_test
business.industry
Myeloid leukemia
First line treatment
Imatinib mesylate
Therapeutic drug monitoring
hemic and lymphatic diseases
Internal medicine
Immunology
medicine
biology.protein
Trough level
business
neoplasms
Pharmacogenetics
Subjects
Details
- ISSN :
- 15277755 and 0732183X
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Oncology
- Accession number :
- edsair.doi...........ea4f7c73b4a43ed84bccf7eab2ddc164
- Full Text :
- https://doi.org/10.1200/jco.2015.33.15_suppl.e13564