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Antifungal efficacy of Brazilian green propolis extracts and honey on Tinea capitis and Tinea versicolor

Authors :
Takao Saruta
Ryoji Hirota
Naoko Kumagai
Basilua Andre Muzembo
Narufumi Suganuma
Masamitsu Eitoku
Muaka Anselme Mbenza
Luzitu Severin Nangana
Tomomi Matsui
Nlandu Roger Ngatu
Source :
European Journal of Integrative Medicine. 3:e281-e287
Publication Year :
2011
Publisher :
Elsevier BV, 2011.

Abstract

Aim of the study This study aimed to determine the prevalence of Tinea capitis and Tinea versicolor , and evaluate the efficacy of bee products in management of skin disorders in Congolese school children. Methodology Medical screening and care for skin disorders were carried out in five Congolese schools from November 2010 to April 2011. Hematological and mycological analyses were performed. Of the 2728 children, there were 305 patients with either Tinea capitis or Tinea versicolor . Of them, 242 eligible patients were randomly allocated to one of the following topical treatment arms: 2% Miconazole ; 50 mg/ml Brazilian green propolis extracts (BPE); 100 mg/ml BPE; Acasia honey or Vaseline. Oneway ANOVA test was performed to assess the significance of the difference between treatment groups at baseline (day 1), adjusting for age, gender and the severity score of skin symptoms. Unpaired t -test was performed to assess the difference between treatments in terms of skin symptoms improvement, WBC count, leukocytes and erythrocytes sedimentation rate (ESR) on day 28 of treatment. Results This study showed that Miconazole ( p p Miconazole and Acasia honey ( p Conclusions Brazilian green propolis extracts improved skin lesions as efficiently as did Miconazole and may serve as an alternative treatment for Tinea mycosis .

Details

ISSN :
18763820
Volume :
3
Database :
OpenAIRE
Journal :
European Journal of Integrative Medicine
Accession number :
edsair.doi...........ea2606fa26e4af86eebd344268d60391
Full Text :
https://doi.org/10.1016/j.eujim.2011.10.001