Inhibitory Effects of the Constituents of Hippophae rhamnoides on 3T3-L1 Cell Differentiation and Nitric Oxide Production in RAW264.7 Cells

Three new flavonol glycosides, hippophaeosides A-C (1-3), together with 27 known constituents, were isolated from Hippophae rhamnoides L. leaves. Their structures were determined by spectroscopic analyses. Their inhibitory activities on 3T3-L1 preadipocyte differentiation and triglyceride accumulation in maturing adipocytes, and nitric oxide production in RAW264.7 cells were examined.